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The Journal of Thoracic and Cardiovascular Surgery, Vol 86, 912-919, Copyright © 1983 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association


ARTICLES

Light and electron microscopic evaluation of canine hearts orthotopically transplanted after 24 hours of extracorporeal preservation

M Tago, R Subramanian and MP Kaye

The hearts of 19 dogs were subjected to in vitro, moderately hypothermic, whole blood perfusion through the aorta for 24 hours. Sixteen of the hearts were reimplanted into recipient animals in the conventional orthotopic fashion and three were subjected to histologic study without reimplantation. Fourteen of the 16 reimplanted hearts successfully supported the recipients. Histologic and ultrastructural studies of the reimplanted hearts 24 hours and 7 days after implantation demonstrated good preservation of cellular and ultracellular structures. Some mild widening of the interstitium was noted.





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Copyright © 1983 by The American Association for Thoracic Surgery.