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The Journal of Thoracic and Cardiovascular Surgery, Vol 89, 499-507, Copyright © 1985 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
DJ Magilligan Jr, JW Lewis Jr, B Tilley and E Peterson
The porcine bioprosthetic heart valve has been commercially available since
1970 and has been the prosthetic heart valve of choice in our institution
since 1971. Since that time 817 patients with 951 porcine valves have been
discharged from the hospital and were available for long-term follow-up.
Patient survival rates, with operative mortality excluded, were 80% +/-
1.7% (standard error) at 5 years and 68% +/- 2.7% at 10 years. Survival
rates for patients with aortic valve prostheses were 78% +/- 2.8% at 5
years and 57% +/- 5.4% at 10 years; for patients with mitral valve
prostheses, survival rates were 80% +/- 2.2% at 5 years and 69% +/- 3.2% at
10 years. Freedom from thromboembolism for aortic valves was 93% +/- 1.4%
at 5 years and 88% +/- 2.6% at 10 years; for mitral valves the freedom from
degeneration or primary tissue failure for aortic valves was 97% +/- 1.3%
at 5 years and 71% +/- 7.6% at 10 years; for mitral valves these figures
were 96% +/- 1.2% at 5 years and 71% +/- 4.1% at 10 years. Valves in
patients 35 years of age and below had a significantly greater rate of
degeneration (p less than 0.001). After 12 years' experience the porcine
bioprosthetic valve has performed well with regard to patient survival and
low rate of thromboembolism. For patients older than 35 years the freedom
from primary tissue failure is 80% at 10 years.
ARTICLES
The porcine bioprosthetic valve. Twelve years later
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