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The Journal of Thoracic and Cardiovascular Surgery, Vol 94, 163-174, Copyright © 1987 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
MA Acker, WA Anderson, RL Hammond, AJ Chin, JW Buchanan, CC Morse, AM Kelly and LW Stephenson
Skeletal muscle ventricles were constructed from canine latissimus dorsi
and connected to the thoracic aorta in six dogs. These ventricles were
stimulated to contract synchronously during diastole. The skeletal muscle
ventricles were capable of continuous stroke work when placed within the
arterial circulation for several weeks. Effective synchronous diastolic
counterpulsation was produced. These results demonstrate that diastolic
counterpulsators can be constructed from skeletal muscle and in the future
may provide a feasible therapeutic alternative for the treatment of
end-stage cardiac failure.
ARTICLES
Skeletal muscle ventricles in circulation. One to eleven weeks' experience
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