HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Balderman, S. C. Articles by Weinblatt, G. Search for Related Content PubMed PubMed Citation Articles by Balderman, S. C. Articles by Weinblatt, G.

The Journal of Thoracic and Cardiovascular Surgery, Vol 94, 434-441, Copyright © 1987 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Tracheal autograft revascularization

SC Balderman and G Weinblatt

A series of experiments were conducted to assess the possibility of revascularizing tracheal homografts with an omental pedicle flap. Three different experiments were performed. In Group I (N = 4) a ten-ring tracheal allograft was embedded into the greater omentum of a recipient animal for 30 days. At reexploration these four allografts were found to have been transformed into a tube consisting mainly of connective tissue. To provide more collateral circulation, we immediately reanastomosed an eight-ring tracheal autograft in Group II animals (N = 7). Collateral blood supply was possibly available from the surrounding mediastinal tissues, the recipient trachea, and the transposed omental graft. Tracheal malacia and loss of rings 4,5, and 6 was a consistent finding and cause of death. A third group of animals (Group III) underwent a similar operation with the addition of free bone grafts being applied to the external surface of the autograft to impede significant tracheal stenosis. The long-term results and the findings when the animals were put to death were the same as in Group II. We conclude that the omental pedicle graft cannot sustain chondrocyte viability. Thus a reliable method for revascularization of a tracheal transplant remains to be found.

This article has been cited by other articles:

				L. F. Tintinago, D. A. Herrera, E. Medina, J. H. Patino, F. Cano, and C. S. Restrepo Ultrasonographic Evaluation of a Vascularized Tracheal Transplantation J. Ultrasound Med., August 1, 2005; 24(8): 1145 - 1149. [Full Text] [PDF]

				W. Klepetko, G. M. Marta, W. Wisser, E. Melis, A. Kocher, G. Seebacher, C. Aigner, and S. Mazhar Heterotopic tracheal transplantation with omentum wrapping in the abdominal position preserves functional and structural integrity of a human tracheal allograft J. Thorac. Cardiovasc. Surg., March 1, 2004; 127(3): 862 - 867. [Abstract] [Full Text] [PDF]

				H. C. Grillo Tracheal replacement: a critical review Ann. Thorac. Surg., June 1, 2002; 73(6): 1995 - 2004. [Abstract] [Full Text] [PDF]

				P. J. Gannon, P. D. Costantino, E. A. Lueg, J. M. Chaplin, M. S. Brandwein, P. J. Passalaqua, L. J. Fliegelman, J. T. Laitman, S. Marquez, and M. L. Urken Use of the Peritracheal Fold in the Dog Tracheal Transplantation Model Arch Otolaryngol Head Neck Surg, September 1, 1999; 125(9): 959 - 963. [Abstract] [Full Text] [PDF]

				K. Murai, H. Oizumi, T. Masaoka, T. Fujishima, M. Abiko, S. Shiono, and Y. Shimazaki Removal of cartilage rings of the graft and omentopexy for extended tracheal autotransplantation Ann. Thorac. Surg., March 1, 1999; 67(3): 776 - 780. [Abstract] [Full Text] [PDF]

				E. Jadczuk High doses of hydrocortisone improved tracheal autograft revascularization Eur. J. Cardiothorac. Surg., December 1, 1998; 14(6): 615 - 620. [Abstract] [Full Text] [PDF]

				T. Mukaida, N. Shimizu, M. Aoe, A. Andou, H. Date, and S. Moriyama Origin of regenerated epithelium in cryopreserved tracheal allotransplantation Ann. Thorac. Surg., July 1, 1998; 66(1): 205 - 208. [Abstract] [Full Text] [PDF]

				J. Li, P. Xu, and H. Chen Successful Tracheal Autotransplantation With Two-Stage Approach Using the Greater Omentum Ann. Thorac. Surg., July 1, 1997; 64(1): 199 - 202. [Abstract] [Full Text]

				J. Li, P. Xu, H. Chen, Z. Yang, and Q. Zhang Improvement of Tracheal Autograft Survival With Transplantation Into the Greater Omentum Ann. Thorac. Surg., December 1, 1995; 60(6): 1592 - 1596. [Abstract] [Full Text]

				P. Macchiarini, G.-M. Mazmanian, V. de Montpreville, E. Dulmet, M. Fattal, B. Lenot, A. Chapelier, P. Dartevelle, and f. t. P.-S. U. L. T. Group EXPERIMENTAL TRACHEAL AND TRACHEOESOPHAGEAL ALLOTRANSPLANTATION J. Thorac. Cardiovasc. Surg., October 1, 1995; 110(4): 1037 - 1046. [Abstract] [Full Text]

				P. R. Delaere, Z. Y. Liu, R. Hermans, R. Sciot, and L. Feenstra Experimental tracheal allograft revascularization and transplantation J. Thorac. Cardiovasc. Surg., September 1, 1995; 110(3): 728 - 737. [Abstract] [Full Text]

				P. Macchiarini, B. Lenot, V. de Montpreville, E. Dulmet, G.-M. Mazmanian, M. Fattal, F. Guiard, A. Chapelier, P. Dartevelle, and f. t. P.-S. U. L. T. Group Heterotopic pig model for direct revascularization and venous drainage of tracheal allografts J. Thorac. Cardiovasc. Surg., December 1, 1994; 108(6): 1066 - 1075. [Abstract] [Full Text]

				H. Yokomise, K. Inui, H. Wada, T. Goh, K. Yagi, S. Hitomi, and M. Takahashi High-dose irradiation prevents rejection of canine tracheal allografts J. Thorac. Cardiovasc. Surg., June 1, 1994; 107(6): 1391 - 1397. [Abstract] [Full Text]