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The Journal of Thoracic and Cardiovascular Surgery, Vol 94, 571-581, Copyright © 1987 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Y Louagie, T Alouini, J Lesperance and LC Pelletier
From 1979 to 1985, 109 patients were treated for congestive heart failure
caused by postinfarction left ventricular aneurysm. Congestive heart
failure was predominant in all patients at the time of diagnosis, 73% of
whom were in Functional Class III or IV. Left ventricular end- diastolic
pressure averaged 23.8 +/- 0.8 mm Hg (mean +/- standard error of the mean),
total ejection fraction 29.7% +/- 1.0%, and telediastolic volume of the
aneurysm 76.2 +/- 5.8 ml. Aneurysmectomy was performed in 49 patients
(45%), whereas the remaining 60 patients were treated medically. The two
groups did not differ in regard to clinical and hemodynamic data on
admission, except for a more extensive coronary artery disease in the
surgical group. Follow-up was obtained for all patients (100%) and averaged
48 +/- 3 months. Actuarial survival curves were similar, and the 5-year
survival rates for surgical and medical groups were 70 +/- 7% and 64% +/-
7%, respectively (not significant). However, the 5-year complication-free
rate was significantly (p = 0.05) higher among surgical patients (52% +/-
8%) than among the medical group (31% +/- 7%). Multivariate analysis showed
the following variables to influence survival independently (p less than
0.05): contractile segment ejection fraction, right ventricular failure,
antecedents of cardiac arrest or cardiogenic shock, and corrected
contractile score. Independent variables decreasing the risk of cardiac-
related complications and death (p less than 0.05) were as follows:
surgical treatment, shorter interval between initial infarction and
diagnosis of aneurysm, and absence of right ventricular failure. Functional
improvement was directly related to surgical treatment and to residual
segment contractile score (p less than 0.05). Thus, in patients with
congestive heart failure caused by left ventricular aneurysm, surgical
treatment improved the quality of life and prognosis for cardiac-related
complications, but did not increase overall survival, compared to medical
management of similar patients.
ARTICLES
Left ventricular aneurysm with predominating congestive heart failure. A comparative study of medical and surgical treatment
Department of Surgery, Montreal Heart Institute, Quebec, Canada.
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