HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by McGrath, L. B. Articles by Gonzalez-Lavin, L. Search for Related Content PubMed PubMed Citation Articles by McGrath, L. B. Articles by Gonzalez-Lavin, L.

The Journal of Thoracic and Cardiovascular Surgery, Vol 94, 582-590, Copyright © 1987 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Actuarial survival, freedom from reoperation, and other events after repair of atrioventricular septal defects

LB McGrath and L Gonzalez-Lavin
Department of Surgery, Deborah Heart and Lung Center, Browns Mills, N.J. 08015.

Repair of an atrioventricular septal defect was performed in 134 patients from 1973 to 1985. Interventricular communication was present in 54 (40%) and none was present in 80 (60%). There were 12 hospital deaths (9%; 70% confidence limits 6%-12%). Earlier date of operation (p = 0.03) and younger age at repair (p = 0.005) were incremental risk factors for hospital death after repair of partial atrioventricular septal defect. Smaller size (p = 0.003) and longer cross-clamp time (p = 0.002) were risk factors for hospital death in those patients with complete atrioventricular septal defect. Higher preoperative pulmonary vascular resistance was a risk factor for death in both groups (p = 0.007). The 10 year actuarial survival rate was 82% overall. Increasing preoperative severity of left atrioventricular valve incompetence was not a risk factor for early (p = 0.001) or late (p = 0.002) death. The 10 year actuarial freedom from reoperation after repair of partial atrioventricular defects was 85%, and it was 68% for complete atrioventricular defects (p = 0.06). We conclude that the intermediate term results after repair of atrioventricular septal defects are good. Incompetence of the left atrioventricular valve has apparently been neutralized as a risk factor for hospital death in this series. However, the durability of the repair has been disappointing. A policy of earlier repair has been adopted and should improve hospital mortality and permit better preservation of the atrioventricular valve structures with resultant improved late term functional status.

This article has been cited by other articles:

				S. P. Malhotra, F. Lacour-Gayet, M. B. Mitchell, D. R. Clarke, M. L. Dines, and D. N. Campbell Reoperation for left atrioventricular valve regurgitation after atrioventricular septal defect repair. Ann. Thorac. Surg., July 1, 2008; 86(1): 147 - 152. [Abstract] [Full Text] [PDF]

				T. Murashita, T. Kubota, J.-i. Oba, T. Aoki, J. Matano, and K. Yasuda Left atrioventricular valve regurgitation after repair of incomplete atrioventricular septal defect Ann. Thorac. Surg., June 1, 2004; 77(6): 2157 - 2162. [Abstract] [Full Text] [PDF]

				A. Boening, J. Scheewe, K. Heine, J. Hedderich, D. Regensburger, H.-H. Kramer, and J. Cremer Long-term results after surgical correction of atrioventricular septal defects Eur. J. Cardiothorac. Surg., August 1, 2002; 22(2): 167 - 173. [Abstract] [Full Text] [PDF]

				C Wren and J J O'Sullivan Survival with congenital heart disease and need for follow up in adult life Heart, April 1, 2001; 85(4): 438 - 443. [Abstract] [Full Text]

				J. Wetter, N. Sinzobahamvya, C. Blaschczok, A.-M. Brecher, L. M. Gravinghoff, A. A. Schmaltz, and A. E. Urban Closure of the zone of apposition at correction of complete atrioventricular septal defect improves outcome Eur. J. Cardiothorac. Surg., February 1, 2000; 17(2): 146 - 153. [Abstract] [Full Text] [PDF]

				E. Kuralay, E. Ozal, U. Demirkilic, F. Cingoz, and H. Tatar Left atrioventricular valve repair technique in partial atrioventricular septal defects Ann. Thorac. Surg., November 1, 1999; 68(5): 1746 - 1750. [Abstract] [Full Text] [PDF]

				T. Gunther, D. Mazzitelli, C. J. Haehnel, K. Holper, F. Sebening, and H. Meisner Long-Term Results After Repair of Complete Atrioventricular Septal Defects: Analysis of Risk Factors Ann. Thorac. Surg., March 1, 1998; 65(3): 754 - 760. [Abstract] [Full Text] [PDF]

				J. S. Tweddell, S. B. Litwin, S. Berger, D. Z. Friedberg, J. P. Thomas, P. C. Frommelt, M. A. Frommelt, A. N. Pelech, D. A. Lewis, R. T. Fedderly, et al. Twenty-Year Experience With Repair of Complete Atrioventricular Septal Defects Ann. Thorac. Surg., August 1, 1996; 62(2): 419 - 424. [Abstract] [Full Text]

				C. Baufreton, D. Journois, F. Leca, W. Khoury, D. Tamisier, and P. Vouhe TEN-YEAR EXPERIENCE WITH SURGICAL TREATMENT OF PARTIAL ATRIOVENTRICULAR SEPTAL DEFECT: RISK FACTORS IN THE EARLY POSTOPERATIVE PERIOD J. Thorac. Cardiovasc. Surg., July 1, 1996; 112(1): 14 - 20. [Abstract] [Full Text]

				K. Bando, M. W. Turrentine, K. Sun, T. G. Sharp, G. J. Ensing, A. P. Miller, K. A.Kesler, R. S. Binford, G. N. Carlos, R. A. Hurwitz, et al. SURGICAL MANAGEMENT OF COMPLETE ATRIOVENTRICULAR SEPTAL DEFECTSA twenty-year experience J. Thorac. Cardiovasc. Surg., November 1, 1995; 110(5): 1543 - 1554. [Abstract] [Full Text]

				H. Miyamura, S. Eguchi, H. Watanabe, H. Kanazawa, M. Sugawara, S. Tatebe, M. Shinonaga, and J.-i. Hayashi Total circular annuloplasty with absorbable suture for the repair of left atrioventricular valve regurgitation in atrioventricular septal defect J. Thorac. Cardiovasc. Surg., June 1, 1994; 107(6): 1428 - 1431. [Abstract] [Full Text]