The Journal of Thoracic and Cardiovascular Surgery, Vol 95, 142-145, Copyright © 1988 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Simultaneous aortic and mitral valve replacement for lupus endocarditis: report of a case and review of the literature
T Moynihan, R Hansen, P Troup and G Olinger
Department of Medicine, Medical College of Wisconsin, Milwaukee.
Severe aortic and mitral valvular insufficiency developed in a 52-year- old
woman with systemic lupus erythematosis after previous treatment with
corticosteroids, splenectomy, and cyclophosphamide for immune
thrombocytopenia and hemolytic anemia. After aggressive management of the
thrombocytopenia, simultaneous prosthetic replacement of both valves was
satisfactorily performed; pathologic examination revealed myxoid
degeneration. The patient was doing well with excellent valve function 26
months after the operation. The relationship of steroid therapy to lupus
valvulitis is reviewed.