The Journal of Thoracic and Cardiovascular Surgery, Vol 96, 299-303, Copyright © 1988 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Experimental evaluation of atriopulmonary anastomosis in the presence of high pulmonary resistance
P Fantidis, C Gamalla Amat, MA Fernandez Ruiz, R Madero Jarabo, F Moreno Granados, D Rubio, E Sanz Galeote and E De Miguel
Department of Pathology, Hospital La Paz, Universidad Autonoma, Madrid, Spain.
We studied pulmonary resistance as a surgical criterion for atriopulmonary
shunt. We created a model of experimental pulmonary hypertension by
establishing a systemic-pulmonary shunt in 11 dogs. Two to 3 months after
the shunt operation, total pulmonary resistance was calculated before (7.24
+/- 1.54 U . m2) and after (3.50 +/- 1.54 U . m2) ligation of the shunt. An
atriopulmonary anastomosis technique was then performed and the hemodynamic
status of the dogs during the first 2 postoperative hours was evaluated.
Pathologic study of the lungs disclosed no arterial lesions. From our
experimental work, we conclude that the surgical criterion for establishing
the indication for this operation should be pulmonary resistance, which is
conditioned by the state of the intrapulmonary vessels. We propose a
procedure for determining real pulmonary resistance in the course of
preoperative catheterization.