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The Journal of Thoracic and Cardiovascular Surgery, Vol 96, 925-929, Copyright © 1988 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Removal of surgically induced fibrous arterial plaques by argon ion laser angiosurgery using a multifiber delivery system. An experimental study in the dog

BT Kjellstrom, AL Bylock, C Bott-Silverman, GL Engelmann, RG Gerrity, C Kittrell, RM Cothren, GB Hayes, MS Feld and JR Kramer
Research Institute, Cleveland Clinic Foundation, Ohio.

Removal of intravascular atherosclerotic obstructions by laser irradiation has gained the attention of many investigators, but has proven to be considerably more difficult to accomplish than initially envisioned. We tested, in an animal model, an argon ion laser delivery system that permits control of (1) laser power, (2) exposure time, and (3) laser beam spot size. The study was conducted on surgically, induced focal fibrous plaques in the carotid arteries of nine dogs. Plaque removal, vessel patency, and healing were evaluated angiographically and by light and electron microscopy at intervals up to 60 days after treatment. Results showed that intravascular obstructions could be removed, healing occurred, and vessels remained patent for up to 60 days.




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Copyright © 1988 by The American Association for Thoracic Surgery.