HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Patterson, G. A. Articles by Maurer, J. Search for Related Content PubMed PubMed Citation Articles by Patterson, G. A. Articles by Maurer, J.

The Journal of Thoracic and Cardiovascular Surgery, Vol 99, 14-20, Copyright © 1990 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Airway complications after double lung transplantation. Toronto Lung Transplant Group

GA Patterson, TR Todd, JD Cooper, FG Pearson, TL Winton and J Maurer
Division of Thoracic Surgery and Pulmonary Medicine, University of Toronto, Ontario, Canada.

We have had success with en bloc double lung transplantation in the management of selected patients with end-stage parenchymal pulmonary disease. Airway complications have been more prevalent in our own experience with double lung transplantation than in reports of combined heart-lung transplantation from other centers. Between November 1986 and March 1989, 16 patients underwent double lung transplantation. Allografts were preserved by topical hypothermic immersion in 12 patients and by pulmonary artery flush with cold crystalloid solution in the most recent four patients. Thirteen patients underwent tracheal anastomosis and the most recent three patients underwent bilateral bronchial anastomoses. Fatal ischemic necrosis of the donor trachea and both main bronchi developed in three patients. Preterminal airway ischemia developed in a patient who had systemic sepsis. Partial anastomotic dehiscence, which went on to form fibrous strictures necessitating endoscopic placement of silicone rubber airway stents, developed in two additional patients. Two other patients had late strictures and required subsequent placement of bifurcation stents. There was no relationship between development of airway complications and gas exchange in the donor lungs, lung ischemic time, early postoperative gas exchange, early postoperative mean pulmonary artery pressure, or frequency of early postoperative rejection. Severe postoperative hypotension occurred in five of eight patients with airway complications and in three of eight patients without airway complications.

This article has been cited by other articles:

				A. Macedo, E. Fadel, G.-M. Mazmanian, V. de Montpreville, M. German-Fattal, S. Mussot, A. Chapelier, and P. G. Dartevelle Heterotopic en bloc tracheobronchial transplantation with direct revascularization in pigs J. Thorac. Cardiovasc. Surg., June 1, 2004; 127(6): 1593 - 1601. [Abstract] [Full Text] [PDF]

				C. L. Lau, G. A. Patterson, and S. M. Palmer Critical Care Aspects of Lung Transplantation J Intensive Care Med, March 1, 2004; 19(2): 83 - 104. [Abstract] [PDF]

				F. Venuta, E. A. Rendina, T. De Giacomo, A. M. Ciccone, M. Moretti, E. Mercadante, M. Anile, and G. F. Coloni Bilateral sequential lung transplantation without sternal division Eur. J. Cardiothorac. Surg., June 1, 2003; 23(6): 894 - 897. [Abstract] [Full Text] [PDF]

				A. G. KADITIS, M. GONDOR, P. A. NIXON, S. WEBBER, R. J. KEENAN, R. KAYE, and G. KURLAND Airway Complications Following Pediatric Lung and Heart-Lung Transplantation Am. J. Respir. Crit. Care Med., July 1, 2000; 162(1): 301 - 309. [Abstract] [Full Text]

				S. Taghavi, T. Birsan, A. Pereszlenyi, N. Kupilik, E. Deviatko, W. Wisser, H. Steltzer, and W. Klepetko Bilateral lung transplantation via two sequential anterolateral thoracotomies Eur. J. Cardiothorac. Surg., May 1, 1999; 15(5): 658 - 662. [Abstract] [Full Text] [PDF]

				S. Taghavi, T. Birsan, R. Seitelberger, N. Kupilik, P. Mares, A. Zuckermann, and W. Klepetko Initial experience with two sequential anterolateral thoracotomies for bilateral lung transplantation Ann. Thorac. Surg., May 1, 1999; 67(5): 1440 - 1443. [Abstract] [Full Text] [PDF]

				J. Bitu-Moreno, I. Francischetti, R. Siemer, G. Matheis, R. Baretti, F.H.A. Maffei, B. Kreitmayr, and F. Beyersdorf Influence of different routes of flush perfusion on the distribution of lung preservation solutions in parenchyma and airways Eur. J. Cardiothorac. Surg., April 1, 1999; 15(4): 481 - 489. [Abstract] [Full Text] [PDF]

				M. A. Norgaard, C. B. Andersen, and G. Pettersson Airway epithelium of transplanted lungs with and without direct bronchial artery revascularization Eur. J. Cardiothorac. Surg., January 1, 1999; 15(1): 37 - 44. [Abstract] [Full Text] [PDF]

				U. Herold, H. Jakob, M. Kamler, R. Thiele, U. Tochtermann, J. Weinmann, J. Motsch, M. M. Gebhard, and S. Hagl Interruption of bronchial circulation leads to a severe decrease in peribronchial oxygen tension in standard lung transplantation technique Eur. J. Cardiothorac. Surg., February 1, 1998; 13(2): 176 - 183. [Abstract] [Full Text] [PDF]

				A. Sundset, S. Tadjkarimi, A. Khaghani, K. Kvernebo, and M. H. Yacoub Human En Bloc Double-Lung Transplantation: Bronchial Artery Revascularization Improves Airway Perfusion Ann. Thorac. Surg., March 1, 1997; 63(3): 790 - 795. [Abstract] [Full Text]

				M. A. Norgaard, P. S. Olsen, U. G. Svendsen, and G. Pettersson Revascularization of the Bronchial Arteries in Lung Transplantation: An Overview Ann. Thorac. Surg., October 1, 1996; 62(4): 1215 - 1221. [Abstract] [Full Text]

				G. Rabago, J. G. Copeland III, F. Rosapepe, A. C. Tsen, D. A. Arzouman, F. A. Arabia, and G. K. Sethi Heart-Lung Transplantation in Situs Inversus Ann. Thorac. Surg., July 1, 1996; 62(1): 296 - 298. [Abstract] [Full Text]

				J. C. Baldwin Invited letter concerning: Double lung transplantation in situs inversus with Kartagener's syndrome J. Thorac. Cardiovasc. Surg., November 1, 1994; 108(5): 992 - 993. [Full Text]

				P. Macchiarini, A. Chapelier, P. Vouhe, J. Cerrina, F. Le Roy Ladurie, F. Parquin, F. Brenot, G. Simonneau, P. Dartevelle, and for the Paris-Sud University Lung Transplant Group Double lung transplantation in situs inversus with Kartagener's syndrome J. Thorac. Cardiovasc. Surg., July 1, 1994; 108(1): 86 - 91. [Abstract] [Full Text]

				H.-J. Schafers, C. M. Schafer, C. Zink, A. Haverich, and H. G. Borst Surgical treatment of airway complications after lung transplantation J. Thorac. Cardiovasc. Surg., June 1, 1994; 107(6): 1476 - 1480. [Abstract] [Full Text]

				B. P. Griffith, M. J. Magee, I. F. Gonzalez, R. Houel, J. M. Armitage, R. L. Hardesty, B. G. Hattler, P. F. Ferson, R. J. Landreneau, and R. J. Keenan Anastomotic pitfalls in lung transplantation J. Thorac. Cardiovasc. Surg., March 1, 1994; 107(3): 743 - 754. [Abstract] [Full Text]

				M. R. Kramer, S. E. Marshall, V. A. Starnes, P. Gamberg, Z. Amitai, and J. Theodore Infectious Complications in Heart-Lung Transplantation: Analysis of 200 Episodes Arch Intern Med, September 13, 1993; 153(17): 2010 - 2016. [Abstract] [PDF]