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The Journal of Thoracic and Cardiovascular Surgery, Vol 99, 651-657, Copyright © 1990 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
BW Lytle, SS Mahfood, DM Cosgrove and FD Loop
From 1978 through 1987, 225 patients underwent operations that included
replacement of the ascending aorta. One hundred twenty-three patients
underwent composite aortic valve and ascending aortic replacement, 30 had
aortic valve replacement with separate graft replacement of the ascending
aorta, and 72 underwent replacement of the ascending aorta without aortic
valve replacement. Thirty-one (13.8%) in-hospital deaths occurred.
Univariate testing of preoperative and operative variables followed by
logistic regression analyses identified miscellaneous aortic disease,
coronary artery bypass grafting, aortic arch replacement, emergency
operation, surgical date (1978 to 1983), and age (all p less than 0.05) as
factors having independent association with in-hospital mortality.
Follow-up of in-hospital survivors (mean interval 46 months, range 8 to 123
months) documented an overall 5-year survival rate of 76%, 83% after
primary operation and 37% after reoperation. Univariate analyses followed
by multivariate testing indicated that previous operation (p less than
0.0001) and a history of preoperative neurologic symptoms (p = 0.021) were
associated with decreased late survival. At follow-up 88% of late survivors
were free of symptoms. Seven patients have undergone reoperation 1 day to
69 months postoperatively. Although the in-hospital mortality for
operations that include ascending aortic replacement exceeds that for
isolated aortic valve replacement, the late death rate and rate of
reoperation are low.
ARTICLES
Replacement of the ascending aorta. Early and late results
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, OH 44195.
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