| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J Thorac Cardiovasc Surg 2001;122:1255-1256
© 2001 The American Association for Thoracic Surgery
Brief Communications |
From the Departments of Cardiovascular Surgerya and Emergency Medicine,b Saga Prefectural Hospital, Koseikan, Saga, Japan.
Received for publication March 21, 2001. Accepted for publication April 24, 2001. Address for reprints: Kojiro Furukawa, Department of Thoracic and Cardiovascular Surgery, Saga Medical School, 5-1-1 Nabeshima, Saga City 849-8501, Japan (E-mail: furukawk@post.saga-med.ac.jp).
The anticoagulant effect of heparin is dependent on the level of antithrombin III (AT III). Argatroban (Novastan; Mitsubishi Tokyo Chemical Corporation, Tokyo, Japan) is a unique synthetic direct thrombin inhibitor developed in Japan.
1 Argatroban requires no AT III to exert its antithrombin effect. 2,3 We used this drug as an anticoagulant during cardiopulmonary bypass (CPB) in a patient with AT III deficiency.
Clinical summary
A 44-year-old man was transferred to our hospital with shock and multiorgan failure on December 31, 1999. Laboratory studies of his blood revealed severe liver dysfunction probably due to fulminant hepatitis. Echocardiography revealed severe aortic regurgitation and vegetations on the aortic valve, and infective endocarditis was diagnosed. Continuous hemodialysis and filtration for renal failure were performed for 12 days and plasma exchange for hepatic failure was performed twice. Gradually, his general condition improved. Aortic valve replacement was scheduled for March 21, 2000. A preoperative echocardiogram showed that the left ventricular diameter was 67.0 mm during diastole and 43.3 mm during systole, and the left ventricular
This article has been cited by other articles:
|
|
 |
|
  T. Okamura, T. Shin'oka, N. Ishibashi, H. Ishii, and H. Kurosawa Simultaneous Use of Argatroban and Heparin during Cardiopulmonary Bypass Asian Cardiovasc Thorac Ann, February 1, 2010; 18(1): 22 - 26. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. I. Smith, R. Stroud, P. Damiani, and M. Vaynblat Use of Argatroban for anticoagulation during cardiopulmonary bypass in a patient with heparin allergy Eur J Cardiothorac Surg, November 1, 2008; 34(5): 1113 - 1114. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. F. Merry Focus on Thrombin: Alternative Anticoagulants Seminars in Cardiothoracic and Vascular Anesthesia, December 1, 2007; 11(4): 256 - 260. [Abstract] [PDF]
|
|
|
|
 |
|
 L. H. Edmunds Jr and R. W. Colman Thrombin During Cardiopulmonary Bypass Ann. Thorac. Surg., December 1, 2006; 82(6): 2315 - 2322. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. D. Iannoli, M. P. Eaton, and J. R. Shapiro Bidirectional Glenn Shunt Surgery Using Lepirudin Anticoagulation in an Infant with Heparin-Induced Thrombocytopenia with Thrombosis Anesth. Analg., July 1, 2005; 101(1): 74 - 76. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. D. Rubens, G. Lavalee, M. A. Ruel, T. Mesana, and M. Bourke Delayed Thrombin Generation With Hirudin Anticoagulation During Prolonged Cardiopulmonary Bypass Ann. Thorac. Surg., January 1, 2005; 79(1): 334 - 336. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. T. Gurbuz, W. G. Elliott, and A. A. Zia Heparin-induced thrombocytopenia in the cardiovascular patient: diagnostic and treatment guidelines Eur J Cardiothorac Surg, January 1, 2005; 27(1): 138 - 149. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Furukawa and H. Ohteki Argatroban as a Heparin Substitute in Cases of Heparin-Induced Thrombocytopenia Ann. Thorac. Surg., December 1, 2004; 78(6): 2208 - 2208. [Full Text] [PDF]
|
|
|
|
|
|
T. E. Warkentin and A. Greinacher Reply Ann. Thorac. Surg., December 1, 2004; 78(6): 2208 - 2209. [Full Text] [PDF]
|
|
|
|
 |
|
 A. K. Wittkowsky Anticoagulation in Hypercoagulable Conditions: Special Considerations in the Treatment and Prevention of Venous Thromboembolism Journal of Pharmacy Practice, October 1, 2004; 17(5): 308 - 316. [Abstract] [PDF]
|
|
|
|
|
|
K. Rikitake, Y. Okazaki, K. Naito, S. Ohtsubo, M. Natsuaki, and T. Itoh Heparinless cardiopulmonary bypass with argatroban in dogs Eur J Cardiothorac Surg, May 1, 2004; 25(5): 819 - 824. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. T. Edwards, J. K. Hamby, and N. K. Worrall Successful use of argatroban as a heparin substitute during cardiopulmonary bypass: heparin-induced thrombocytopenia in a high-risk cardiac surgical patient Ann. Thorac. Surg., May 1, 2003; 75(5): 1622 - 1624. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. R. Kieta, A. T. McCammon, W. L. Holman, and V. G. Nielsen Hemostatic Analysis of a Patient Undergoing Off-Pump Coronary Artery Bypass Surgery with Argatroban Anticoagulation Anesth. Analg., April 1, 2003; 96(4): 956 - 958. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Lubenow, S. Selleng, H.-G. Wollert, P. Eichler, B. Mullejans, and A. Greinacher Heparin-induced thrombocytopenia and cardiopulmonary bypass: perioperative argatroban use Ann. Thorac. Surg., February 1, 2003; 75(2): 577 - 579. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. Vasquez, A. Vichiendilokkul, S. Mahmood, and F. A. Baciewicz Jr Anticoagulation with bivalirudin during cardiopulmonary bypass in cardiac surgery Ann. Thorac. Surg., December 1, 2002; 74(6): 2177 - 2179. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. K. Young New Treatment Options for Heparin-Induced Thrombocytopenia Journal of Pharmacy Practice, August 1, 2002; 15(4): 305 - 317. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
