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J Thorac Cardiovasc Surg 2002;123:582-583
© 2002 The American Association for Thoracic Surgery

Letters to the Editor

Cellular myoplasty: What are we really trying to achieve?

Robert C. Gorman, MD, Joseph H. Gorman, III, MD

University of Pennsylvania Medical School
Philadelphia, PA 19104

To the Editor:

The article by Rajnoch and associatesGo 1 and the associated editorial by Weisel and colleaguesGo 2 in the May 2001 issue of the Journal add to a rapidly expanding body of literature assessing the efficacy of "cellular cardiomyoplasty" in preventing or reversing heart failure due to postinfarction left ventricular remodeling.

The implied hypothesis is that cellular cardiomyoplasty replaces cardiac myocytes that have been lost as a result of a myocardial infarction. . . . [Full Text of this Article]




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M. Rubart, K. B.S. Pasumarthi, H. Nakajima, M. H. Soonpaa, H. O. Nakajima, and L. J. Field
Physiological Coupling of Donor and Host Cardiomyocytes After Cellular Transplantation
Circ. Res., June 13, 2003; 92(11): 1217 - 1224.
[Abstract] [Full Text] [PDF]


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