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J Thorac Cardiovasc Surg 2003;126:1188-1190
© 2003 The American Association for Thoracic Surgery

Brief communication

Does bridging to transplantation with a left ventricular assist device adversely affect posttransplantation survival? A comparative analysis of mechanical versus inotropic support

^a Department of Surgery, Division of Cardiothoracic Surgery, College of Physicians and Surgeons, Columbia University, New York, NY USA

Received for publication April 1, 2003; accepted for publication June 3, 2003.

^* Address for reprints: Yoshifumi Naka, MD, PhD, Columbia University, College of Physicians and Surgeons, 177 Fort Washington Ave, Milstein Hospital 7GN-435, New York, NY 10032, USA
yn33@columbia.edu

The first 20% of the full text of this article appears below.

Implantation of a left ventricular assist device (LVAD) as a bridge to transplantation has become an acceptable intervention in patients with end-stage heart failure.^1,2 Patients bridged to transplantation with LVADs have demonstrated improvements in blood pressure, hepatic function, renal function, physical function, and quality of life.^3,4 However, whether mechanical support adversely affects posttransplantation survival is still controversial.⁵ Do patients bridged to transplantation with an LVAD demonstrate decreased posttransplantation survival compared with patients bridged with inotropic support? The aim of this study was to answer this question.

Patients and methods

We retrospectively reviewed our experience at Columbia Presbyterian Medical Center with bridge-to-transplantation patients from June 1996 through September 2002. During this time period, 266 patients in United Network for Organ Sharing status 1 were successfully bridged to transplantation by either mechanical (n = 121, 45.7%) or inotropic (n = 145, 54.5%) support. LVAD support was provided by the HeartMate single-lead vented electric device (Thoratec, Pleasanton, Calif). Posttransplantation survival at . . . [Full Text of this Article]

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