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J Thorac Cardiovasc Surg 2003;126:1674-1675
© 2003 The American Association for Thoracic Surgery
Letters to the editor |
a Division of Cardiology and Critical Care Medicine, Hospital for Sick Children, University of TorontoToronto, Ontario M5G 1X8, Canada
b National Jewish Medical and Research Center, Denver, CO 80206 USA
| The first 20% of the full text of this article appears below. |
Reply to the Editor:
We thank Dr Marczin for his interest in our work1 and the Editor for an opportunity to respond.
The first issue raised concerns the methodology of exhaled nitric oxide (NO) analysis. There are several ways to measure exhaled NO at a constant flow rate in the sedated, intubated, and mechanically ventilated patient. These include syringe aspiration sampling as performed by us,1 tidal breathing profiles, and single-breath controlled-flow techniques.2 The latter is difficult to apply outside the neonatal period. We chose the syringe aspiration sampling method because in our preliminary investigations we found it to be a robust, reproducible technique. Indeed, we confirmed the reproducibility of the method by finding similar
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J. Thorac. Cardiovasc. Surg. 2003 126: 1673-1674.
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