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J Thorac Cardiovasc Surg 2003;126:2112-2113
© 2003 The American Association for Thoracic Surgery

Letter to the editor

Activated prothrombin complex concentrates and recombinant factor VIIa in the bleeding patient: are they appropriate and safe?

Louis M. Aledort, MD

The Mary Weinfeld Professor of Clinical Research in Hemophilia, Mount Sinai School of Medicine, New York, NY 10029, USA

The first 20% of the full text of this article appears below.

To the Editor:

I read with great interest the article of Bui and colleagues,1 "Fatal Thrombosis After Administration of Activated Prothrombin Complex Concentrates in a Patient Supported by Extracorporeal Membrane Oxygenation Who Had Received Activated Recombinant Factor VII," in the October 2002 Journal. Many issues related to the administration of activated prothrombin complex concentrates presented by this case were too simply discussed.

First, the patient had evidence of disseminated intravascular coagulation . . . [Full Text of this Article]






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