JTCS St. Jude Medical
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Theo Kofidis
Robert C. Robbins
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kofidis, T.
Right arrow Articles by Robbins, R. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kofidis, T.
Right arrow Articles by Robbins, R. C.
Related Collections
Right arrow Cardiac - other
Right arrowRelated Article

J Thorac Cardiovasc Surg 2003;126:2113-2114
© 2003 The American Association for Thoracic Surgery

Letter to the editor

A few critical aspects—and Achilles heels—of tissue engineering approaches to restore injured myocardium

Theo Kofidis, MD, Leora B. Balsam, MD, Robert C. Robbins, MD

Cardiothoracic Surgery/Falk Research Center, Stanford University Medical School, Stanford, CA 94305, USA

The first 20% of the full text of this article appears below.

To the Editor:

We enjoyed reading Osawa and colleagues' article about histologic changes of biomaterials used to repair ventricular heart defects in small animals1 as published in this Journal and also have followed this group's work elsewhere.2 Our own review on the current literature in this area has spawned many questions and suggestions for future study designs.

Most published studies do not present clinically applicable, reparative options. We believe that a critical analysis of these studies with respect to geometry, physiology, and inflammatory and immunologic responsiveness of myocardium will help identify flaws in current study designs and also help define standardized quality criteria to guide future attempts to manufacture implantable myocardium.

Few studies, for instance, have reliably and convincingly . . . [Full Text of this Article]


Related Article

Reply to the Editor
Shafie Fazel, Richard D. Weisel, and Ren-Ke Li
J. Thorac. Cardiovasc. Surg. 2003 126: 2114-2115. [Extract] [Full Text] [PDF]





HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2003 by The American Association for Thoracic Surgery.