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J Thorac Cardiovasc Surg 2004;127:289-291
© 2004 The American Association for Thoracic Surgery

Brief communication

Intrasternal respiratory epithelium–lined foregut cyst

Sven Seiwerth, MDa, Corinna Brüschke, MDa, Juergen Wiens, MDa, Helmut Ostertag, MDa, Paolo Macchiarini, MD, PhDb,*

a Department of Pathology, Nordstadt Hospital Hannover, Germany
b Department of Thoracic and Vascular Surgery, Heidehaus Hospital, Hannover, Germany

Received for publication June 7, 2003; accepted for publication July 16, 2003.

* Address for reprints: Paolo Macchiarini, MD, PhD, Department of Thoracic and Vascular Surgery, Heidehaus Hospital, Hannover Medical School, Am Leineufer 70, 30419 Hannover, Germany
pmacchiarini@compuserve.com

The first 20% of the full text of this article appears below.

Foregut or enterogenous cysts are the result of an abnormal budding or division of the primitive foregut and are usually found in adults. On the basis of histologic features and embryogenesis, they are classified into bronchogenic, esophageal, gastroenteric, and neuroenteric cysts and usually occur in the mediastinum or, less frequently, in the soft tissues of the chest wall.1 Intrasternal foregut cysts lined by respiratory epithelium have never previously been described in the literature, and we present here the first case.

Clinical summary

A 61-year-old woman was admitted because of the onset of moderate and recurrent feeling of retrosternal pressure and pain and a cystic lesion of unknown histologic type of the manubrium sterni growing partially into the superior ventral mediastinum up to the aortic arch. Results of physical examination were normal. Conventional tomography and thoracic computed tomography (Figure 1) showed a lesion of the manubrium sterni with impression and sclerosis of the compacta. The intraosseous part of the cyst had a 1- to 2-cm wide connection to a 5 x 3-cm retrosternal extraosseous part. The extraosseous lesion was attached to the aortic arch and was limited by a calcified, enhancing capsule. Calcification of the compacta and smooth bone rimming of the perforated part of the compacta indicated the presence of a long-lasting process. Conventional radiographs of the thorax from 2 and 10 years previously also . . . [Full Text of this Article]






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