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J Thorac Cardiovasc Surg 2004;127:588-589
© 2004 The American Association for Thoracic Surgery


Brief communication

Pulmonary mucormycosis in a patient with chronic obstructive pulmonary disease: Diagnosis by fine needle aspiration cytology

Mustafa Benekli, MDa,*, John K. Cranea, Robert R. Contib, Jayne E. Kremzierc, Rakesh Bidania

a Department of Medicine, State University of New York at Buffalo, Buffalo, NY, USA
b Department of Radiology, State University of New York at Buffalo, Buffalo, NY, USA
c Department of Pathology, State University of New York at Buffalo, Buffalo, NY, USA

Received for publication August 13, 2003; accepted for publication September 9, 2003.

* Address for reprints: Mustafa Benekli, MD, 415 Delta Rd Apt 3, Amherst, NY 14226, USA
mbenekli@lycos.com

The first 20% of the full text of this article appears below.

Pulmonary mucormycosis is a rare opportunistic infection caused by invasive filamentous fungi of the class Zygomycetes belonging to the order Mucorales.1 Mucormycosis most frequently occurs in diabetic individuals, immunosuppressed patients on chronic steroids, patients with hematologic malignancies, or solid organ or bone marrow transplant recipients. There have been only 2 case reports of pulmonary mucormycosis in patients with chronic obstructive pulmonary disease (COPD) who have been treated with oral steroids.2,3

We report a patient with COPD who presented with pulmonary masses. Diagnosis of the mucormycosis was made by fine needle aspiration cytology (FNAC).

Clinical summary

A 72-year-old African-American woman who was a heavy smoker was admitted with shortness of breath and chest pain. She had a myocardial infarction (MI) 8 months previously, which was followed by a double-vessel coronary artery bypass grafting (CABG) surgery. The patient developed deep vein thrombosis and bilateral pulmonary embolism (PE) 2 months after the surgery and was incidentally found to have a spiculated 2.5-cm left lower lobe lung mass in spiral computerized tomography (CT) of the chest. However, further workup of the mass was deferred because of . . . [Full Text of this Article]







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