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J Thorac Cardiovasc Surg 2004;127:606
© 2004 The American Association for Thoracic Surgery

Letter to the editor

Reply to the Editor

Ischemia Research and Education Foundation, San Francisco, CA 94121, USA

The first 20% of the full text of this article appears below.

My colleagues and I thank Dr Katz for his letter. Please find below our responses to his questions.

First, regarding the morphine-sparing effect, we believe that this not only is statistically significant but clinically meaningful for these patients. As you may be aware, patients undergoing coronary artery bypass grafting have impaired pulmonary function, with most having a protracted smoking history and an increasing number having ventricular dysfunction. Contributing as well are the effects of narcotics, particularly when administered early (<12 hours)—that is, at about the time of . . . [Full Text of this Article]

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J. Thorac. Cardiovasc. Surg. 2004 127: 605. [Extract] [Full Text] [PDF]