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J Thorac Cardiovasc Surg 2004;127:892-893
© 2004 The American Association for Thoracic Surgery

Letter to the editor

Reply to the Editor

Rinaldo Bellomo, MD

Department of Intensive Care and Research, Austin Hospital, Melbourne, Victoria , Australia

David L. Hare, MD

Department of Cardiology, Austin Hospital, Melbourne, Victoria, Australia

Brian F. Buxton, MD

Department of Cardiac Surgery, Austin Hospital, Melbourne, Victoria, Australia

The first 20% of the full text of this article appears below.

We thank Professor Angelini and colleagues for raising several important issues in relation to our trial.1 However, we do not agree that the conclusion of our article is misleading, and we believe that the issues raised in their letter can be simply and easily addressed.

The article presents the results 5 years after trial inception. We make that perfectly clear in the text and display the mean duration of follow-up in a graphic format with the Kaplan-Meier graphs. Pocock's concerns about the imprecision of estimates as displayed by such graphs in the presence of few events relates to the risk of conveying a visual impression of a difference where none exists. This is of moot concern in a graphic display of actual lack of difference.2

This interim analysis was not planned; it represented a response of the group of cardiac surgeons, cardiologists, intensivists, and cardiac anesthesiologists involved in the trial to the aggressively promoted view that radial artery conduits are "best," a view also strongly espoused by Professor Angelini . . . [Full Text of this Article]






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