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J Thorac Cardiovasc Surg 2005;129:949-950
© 2005 The American Association for Thoracic Surgery
Brief Communications |
a Division of Pediatric Cardiac Surgery, Bambino Gesù Hospital, Rome, Italy
b Division of Cardiovascular Bioengineering, Istituto Superiore di Sanità, Rome, Italy
c Department of Radiology, S. Andrea Hospital, Rome, Italy
Received for publication August 14, 2004; accepted for publication August 19, 2004. * Address for reprints: Antonio Amodeo, MD, Dipartimento Medico Chirurgico di Cardiologia Pediatrica, Ospedale Bambino Gesù, Piazzale S. Onofrio 4, Rome 00165, Italy (E-mail: antonioamodeo@yahoo.it).
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Patients with single ventricle, left isomerism, and azygos continuation of the inferior vena cava usually undergo a staged cardiac repair comprising a total bidirectional cavopulmonary anastomosis with the exclusion of the hepatic venous return (Kawashima operation) during childhood followed by a complementary hepatic vein-to-pulmonary artery connection (Fontan completion) 2 to 3 years later. The latter step can effectively counteract the progressive cyanosis resulting from both systemic venous collaterals emptying into the low-pressure hepatic venous compartment and pulmonary arteriovenous malformations related to lack of a putative hepatic or splanchnic factor. However, both the intracardiac and the extracardiac conventional pathways for diverting the hepatic venous return to the pulmonary circulation are highly predisposed toward thrombosis.1 This is caused by an intrinsic tendency for deep vein thromboses typical in patients with
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