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J Thorac Cardiovasc Surg 2005;129:1187-1188
© 2005 The American Association for Thoracic Surgery

Brief Communications

Closure of ventricular septal defects in the donor heart before transplantation: Toward expanded acceptance criteria

S. Maltais, MD, MSca,b,c, M. Carrier, MDa,b,c, M. Pellerin, MDa,b,c, L.P. Perrault, MD, PhDa,b,c,*

a Research Center, Montreal Heart Institute, Montreal, Quebec, Canada.
b the Department of Surgery, Montreal Heart Institute, Montreal, Quebec, Canada.
c University of Montreal, Montreal, Quebec, Canada.

Received for publication August 30, 2004; accepted for publication September 7, 2004.

* Address for reprints: L. P. Perrault, MD, PhD, Research Center, Montreal Heart Institute, 5000 Belanger St East, Montreal, Quebec, H1T 1C8 Canada (E-mail: louis.perrault@icm-mhi.org).

The first 20% of the full text of this article appears below.


Figure 1
Dr Perrault


The limited supply and increasing shortage of adequate donor organs for transplantation has been met with expansion of criteria for donor heart acceptance.1

Patent foramen ovale and atrial septal defects have been diagnosed after cardiac transplantations2,3 and have been treated by surgical or transcatheter closure.4 Occasionally, significant right-to-left shunting across a septal patent foramen ovale might result in profound hypoxemia. Residual atrial defects might cause a serious hemodynamic compromise because of shunting and significant tricuspid regurgitation.3 The present report describes 2 successful heart transplantations after concomitant surgical closure of a ventricular septal defect (VSD) in the donor heart.

Clinical summary

Patient 1
A 41-year-old man with no medical history was given a diagnosis of brain death after self-inflicted head trauma, and consent was obtained for multiple . . . [Full Text of this Article]






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