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J Thorac Cardiovasc Surg 2005;129:1197
© 2005 The American Association for Thoracic Surgery

Letters to the Editor

Why clopidogrel failed to inhibit platelet function early after coronary artery bypass surgery: To load or not to load, and is it a question of resistance?

Ian Hunt, MRCSa, Lucy J.H. Blows, MRCPb, Sundip J. Patel, MRCPb

a Department of Cardiothoracic Surgery, St Thomas’ Hospital, London, United Kingdom
b Department of Cardiology, St Thomas’ Hospital, London, United Kingdom

The first 20% of the full text of this article appears below.

To the Editor:

Antiplatelet therapy remains a topic of much-deserved attention and debate. We read with interest the recent article by Lim and associates1 in which they found that clopidogrel after coronary artery bypass grafting failed to inhibit platelet function, on the basis of the percentage platelet aggregation on day 5. Patients were randomized to receive 100 or 325 mg of aspirin daily or . . . [Full Text of this Article]




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