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J Thorac Cardiovasc Surg 2005;129:1204
© 2005 The American Association for Thoracic Surgery

Letters to the Editor

Early ischemic preconditioning provides transient protection

Department of Cardiovascular Surgery, Istanbul University, Istanbul, Turkey

The first 20% of the full text of this article appears below.

To the Editor:

We read with great interest the study by Toumpoulis and colleagues,¹ "Superiority of Early Relative to Late Ischemic Preconditioning in Spinal Cord Protection After Descending Thoracic Aortic Occlusion" published in the November 2004 issue of the Journal. In their experimental model, they revealed the superiority of early ischemic preconditioning (IP) in reducing spinal cord injury caused by thoracic aortic occlusion. IP is a new concept against spinal cord ischemic injury. Although previous reports have demonstrated its beneficial effects, there are still controversial issues including the fundamental mechanisms by which it provides protection . . . [Full Text of this Article]