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J Thorac Cardiovasc Surg 2005;129:1208-1209
© 2005 The American Association for Thoracic Surgery

Letters to the Editor

Reply to the Editor

Paolo Macchiarini, MD, PhD

Division of General Thoracic Surgery, Hospital Clinic de Barcelona, University of Barcelona, Barcelona, Spain

The first 20% of the full text of this article appears below.

It is a distinct privilege to have attracted the interest of Hermes Grillo, and frankly speaking, his comments were expected. In his letter to the Editor, Dr Grillo questions clinical and experimental issues that I am delighted to address.

It is certainly correct that the airway defect could have been closed without the interposition of the engineered airway tissue. However, we all know that (1) it is technically demanding and risky to free (by further devascularizing it) a leaky postradiation (70 Gy) carinal anastomosis, and that (2) an . . . [Full Text of this Article]






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