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J Thorac Cardiovasc Surg 2005;130:1216-1217
© 2005 The American Association for Thoracic Surgery

Brief Communication

A giant pleural fibrous tumor

^a Cardiothoracic Unit, University Hospital of Wales, Cardiff, United Kingdom
^b Histopathology Department, University Hospital of Wales, Cardiff, United Kingdom

Received for publication January 22, 2005; revisions received February 22, 2005; accepted for publication April 5, 2005.

^_* Address for reprints: Heyman Luckraz, FRCS, Cardiothoracic Unit, Block C5, University Hospital of Wales, Heath Park, Cardiff CF14 4XN, UK (Email: HeymanLuckraz@aol.com).

The first 20% of the full text of this article appears below.

Localized (solitary) fibrous tumors of the pleura (LFTPs) were first described as a separate entity in 1931, ¹ despite having first been reported in 1870. ² They represent fewer than 5% of pleural neoplasms, with a prevalence of approximately 2.8 cases per 100,000 hospital patients. Immunohistochemical analysis has confirmed these tumors to be nonmesothelial in origin. ³ They arise from either visceral or parietal pleura and may undergo malignant transformation (as many as 12% of cases). ⁴

Symptoms such as dyspnea, cough, chest pain, arthritic pain, finger clubbing, and hypoglycemia (from production of insulinlike growth factors) are present in 50% of cases, whereas the remainder are discovered incidentally. The heaviest LFTP described to date weighed 1850 g. ⁵ We describe a case of an LFTP that enlarged at an average rate of 10 g/month during a period of 16 years.

Clinical Summary

A 67-year-old woman was referred with a left pleural space-occupying lesion (Figure 1). She had undergone . . . [Full Text of this Article]

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