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J Thorac Cardiovasc Surg 2006;131:250-251
© 2006 The American Association for Thoracic Surgery

Letter to the Editor

Methylene blue revised

Paulo Roberto B. Evora, MD, PhD, Alfredo José Rodrigues, MD, PhD

Division of Thoracic and Cardiovascular Surgery, Ribeirão Preto Faculty of Medicine, University of São Paulo, São Paulo, Brazil

The first 20% of the full text of this article appears below.

To the Editor:

Recently, Taylor and Holtby 1 Go have presented a case of refractory hypotension in a child with native mitral valve endocarditis with cerebral complications in whom methylene blue (MB) was less effective than previously described. 2,3 Go

We have been using MB to treat refractory vasoplegias since 1994, and our experience is corroborated by the specialized medical literature. Most of our experience involved adults who had hypotension during cardiopulmonary bypass (CPB) or after the operation, situation in which, like sepsis, nitric oxide plays a primordial role. 4,5 Go In this milieu two prospective and randomized studies reached positive . . . [Full Text of this Article]


Related Article

Reply to the Editor
Katherine Taylor
J. Thorac. Cardiovasc. Surg. 2006 131: 251. [Extract] [Full Text] [PDF]



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