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J Thorac Cardiovasc Surg 2006;131:252-253
© 2006 The American Association for Thoracic Surgery

Letter to the Editor

Anesthetic preconditioning as the alternative to ischemic preconditioning

Markus Lange, MD, Norbert Roewer, MD, PhD, Franz Kehl, MD, PhD, DEAA

Department of Anesthesiology, University of Würzburg, Würzburg, Germany

The first 20% of the full text of this article appears below.

To the Editor:

We read with interest the article by Canyon and Dobson 1 Go presenting a combination of the adenosine A1 agonist 2-chloro-N6-cyclopentyladenosine (CCPA) and lidocaine as a possibly useful alternative to ischemic preconditioning in the clinical setting. As Canyon and Dobson 1 Go state, "A goal for more than 2 decades has been to develop a pharmacologic mimetic of IPC [ischemic preconditioning] to protect the heart during acute regional ischemia." Canyon and Dobson 1 Go unfortunately did not mention that volatile anesthetics are . . . [Full Text of this Article]






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