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Lorenzo Spaggiari
Domenico Galetta
Francesco Leo
Roberto Gasparri
Francesco Petrella
Alessandro Borri
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J Thorac Cardiovasc Surg 2006;131:490-491
© 2006 The American Association for Thoracic Surgery


Brief Communication

Superior vena cava replacement for lung cancer using a heterologous (bovine) prosthesis: Preliminary results

Lorenzo Spaggiari, MD, PhD a , * , Domenico Galetta, MD a , Giulia Veronesi, MD a , Francesco Leo, MD a , Roberto Gasparri, MD a , Francesco Petrella, MD a , Alessandro Borri, MD a , Giuseppe Pelosi, MD b , Marco Venturino, MD c

a Department of Thoracic Surgery, European Institute of Oncology, Milan, Italy
b Department of Pathology, European Institute of Oncology, Milan, Italy
c Department of Anesthesiology, European Institute of Oncology, Milan, Italy

Received for publication August 23, 2005; revisions received August 26, 2005; accepted for publication September 9, 2005.

* Address for reprints: Lorenzo Spaggiari, MD, PhD, Department of Thoracic Surgery, European Institute of Oncology, via Ripamonti 435, 20141 Milan, Italy (Email: lorenzo.spaggiari@ieo.it).

The first 20% of the full text of this article appears below.


Figure 1
Drs Petrella, Gasparri, Spaggiari, Scanagatta, Veronesi, Galetta, Leo, Borri (left to right)


Superior vena cava (SVC) resection for lung cancer is technically feasible, with encouraging oncologic results when modern selection criteria are used. 1 Go However, some questions still remain, mainly those regarding which type of prosthetic replacement to use after complete SVC substitution. We successfully experimented with a new revascularization technique for SVC replacement after its complete resection for lung cancer, using a heterologous (bovine) custom-made pericardial prosthesis, and we report the early outcome (oncologic and graft patency results) of a preliminary consecutive series.

Clinical Summary

From 1998, 70 patients underwent SVC system resection for lung and mediastinal malignancies: 34 (49%) received prosthetic replacement, and of these, the last 5 patients underwent SVC revascularization with a heterologous (bovine) custom-made pericardial prosthesis.

The surgical approach used was either a large muscle–sparing lateral thoracotomy in the anterior fourth rib section (n = 4) or a right hemiclamshell approach (n = 1). After radical lymph node dissection and before lung resection, . . . [Full Text of this Article]




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