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J Thorac Cardiovasc Surg 2006;131:505-506
© 2006 The American Association for Thoracic Surgery

Letter to the Editor

Triiodothyronine in neonatal heart surgery: Looking for an answer

Nikolaus A. Haas, Christoph K. Camphausen

Paediatric Cardiac Intensive Care, The Prince Charles Hospital, Brisbane, Queensland, Australia

The first 20% of the full text of this article appears below.

To the Editor:

We congratulate Mackie and colleagues 1 Go on their randomized study on triiodothyrodine (T3) treatment in neonatal heart surgery. In their study group the authors correctly enrolled a homogenous group of infants at highest risk of postoperative low cardiac output syndrome and marked thyroid hormone suppression. 2 Go As already shown by several other authors, the thyroid hormone levels are suppressed after cardiopulmonary bypass (CPB), decreasing to a nadir at around 48 hours after CPB and recovering over approximately 1 week. Logically, treatment with T3 after CPB raises the T3 plasma concentrations to normal levels, and no . . . [Full Text of this Article]


Related Article

Reply to the Editor
Andrew S. Mackie, Stephen J. Roth, and Jane W. Newburger
J. Thorac. Cardiovasc. Surg. 2006 131: 506. [Extract] [Full Text] [PDF]





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