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J Thorac Cardiovasc Surg 2006;131:e1-e2
© 2006 The American Association for Thoracic Surgery
Brief Communication |
a Department of Cardiology, The Children's Hospital Boston, Boston, Massachusetts
b Department of Cardiac Surgery, The Children's Hospital Boston, Boston, Massachusetts
c Department of Pediatrics, Harvard Medical School, Boston, Mass
d Department of Surgery, Harvard Medical School, Boston, Mass
Received for publication August 4, 2005; revisions received November 14, 2005; accepted for publication November 16, 2005. * Address for reprints: Emile Bacha, MD, Associate Professor of Surgery, Harvard Medical School, Senior Associate, Department of Cardiac Surgery, Children's Hospital Boston, 300 Longwood Ave. Bader 273, Boston, MA 02115 (Email: emile.bacha@cardio.chboston.org).
| The first 20% of the full text of this article appears below. |
Clinical Summary
A 3.9-kg male child was born at full term following an unremarkable prenatal course. Although initially vigorous he quickly developed respiratory distress and was brought to the neonatal intensive care unit where, upon arrival, he developed profound hypoxemia and respiratory failure. He was intubated and placed on conventional mechanical ventilation. A chest radiograph was interpreted as mild cardiomegaly with diffuse hyaline membrane disease. Umbilical arterial and venous catheters (UVC) were placed and his clinical status rapidly deteriorated. Due to refractory hypoxemia, administration of high-frequency ventilation and nitric oxide was attempted without clinical response. Metabolic acidosis and hypotension ensued and high-dose dopamine and prostaglandin were initiated. An echocardiogram was obtained and demonstrated severe biventricular dysfunction. The left atrium appeared small and the pulmonary veins were not visualized. The patient was transferred to this hospital for further evaluation and care.
Upon arrival to this institution the infant was profoundly hypoxemic (peripheral saturation 44%), acidotic, and hemodynamically labile, with evidence of early end-organ dysfunction. He was immediately cannulated for veno-arterial extracorporeal membrane oxygenation (ECMO) from the right neck.
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