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J Thorac Cardiovasc Surg 2006;131:1226
© 2006 The American Association for Thoracic Surgery

Editorial

Protecting the central nervous system during ischemia: A difficult task

John A. Kern, MD *

University VA Health Sciences Center, Department of Cardiothoracic Surgery, Charlottesville, Va.

Received for publication October 31, 2005; accepted for publication November 1, 2005.

* Address for reprints: John A. Kern, MD, University VA Health Sciences Center, Department of Cardiothoracic Surgery, Box 310-88, Charlottesville, VA 22908. (Email: jkern@virginia.edu; JAK3R@virginia.edu).

The first 20% of the full text of this article appears below.

GoThis issue contains a remarkable study by Kawata and colleagues. 1 Go The prevention of central nervous system (CNS) damage during prolonged hypothermic circulatory arrest has significant ramifications. In this study the authors demonstrated that erythropoietin (EPO) crosses the blood brain barrier and protects the brain and spinal cord from prolonged ischemic injury during hypothermic circulatory arrest. The fact that the animals in this study were . . . [Full Text of this Article]


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Erythropoietin protects the central nervous system during prolonged hypothermic circulatory arrest: An experimental study in a canine model
Mitsuhiro Kawata, Shinichi Takamoto, Kazuo Kitahori, Hiroyuki Tsukihara, Tetsuro Morota, Minoru Ono, Noboru Motomura, Arata Murakami, and Yoshihiro Suematsu
J. Thorac. Cardiovasc. Surg. 2006 131: 1331-1337. [Abstract] [Full Text] [PDF]





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