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J Thorac Cardiovasc Surg 2006;132:203-204
© 2006 The American Association for Thoracic Surgery

Brief Communication

Pathologic features of cryopreserved aortic allograft implanted in the active infection

^a Division of Cardiovascular, Thoracic and Pediatric Surgery, Department of Cardio-Pulmonary and Vascular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
^b Department of Pathology and Tumor Biology, Kyoto University Graduate School of Medicine, Kyoto, Japan

Received for publication January 25, 2006; accepted for publication February 6, 2006.

^_* Address for reprints: Yutaka Okita, MD, Division of Cardiovascular, Thoracic and Pediatric Surgery, Department of Cardio-Pulmonary and Vascular Medicine, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan. (Email: yokita@med.kobe-u.ac.jp).

The first 20% of the full text of this article appears below.

Cryopreserved aortic allografts are believed to be more resistant to infectious circumstances than are synthetic grafts. However, their tolerance against infection remains unclear despite, good clinical outcomes. Few pathologic findings of cryopreserved aortic allografts implanted in active infectious sites have been reported in the literature. ¹ We report our pathologic findings from a cryopreserved aortic allograft that failed to survive in the active infection site.

Clinical Summary

A 67-year-old man with a saccular descending thoracic aortic aneurysm (Figure 1, A) underwent endovascular repair with a covered stent (self-expandable Cook-Z stent 30 mm+ UBE woven graft 30 mm; Cook Incorporated, Bloomington, Ind). Although the stent-grafting was successful, the patient was back at our hospital with high-grade fever 3 weeks after the procedure. The white blood cell count was 8800 cells/µL, with a leftward shift. The serum C-reactive protein level was increased 5.4 mg/dL. A blood culture demonstrated growths of Enterococcus faecalis and Enterobacter cloacae. A computed tomographic scan of the chest showed fluid collection with air retention around the stent-graft. Although . . . [Full Text of this Article]

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