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J Thorac Cardiovasc Surg 2006;132:283-290
© 2006 The American Association for Thoracic Surgery
Cardiopulmonary Support and Physiology |
a Department of Cardiothoracic Surgery, Montefiore-Einstein Heart Center, Bronx, NY
b Departments of Surgery, Medicine, and Community and Family Medicine, Dartmouth Medical School, Hanover, NH
c Department of Anesthesiology and Perioperative Medicine, London Health Sciences Center, London, Ontario, Canada
d Cardiac Surgical Research Group, Flinders Medical Centre, South Australia, Australia
e Department of Cardiothoracic Surgery, Catholic Medical Center, Manchester, NH
f Fresenius Medical Care Extracorporeal Alliance, San Diego, Calif
g Christina Care Health System, Wilmington, Del
h Department of Anesthesiology, Duke Medical Center, Durham, NC
i Department of Perfusion Services, University of Connecticut Health Center, Farmington, Conn
j Beth Israel-Deaconess Medical Center, Boston, Mass
k Green Lane Cardiothoracic Surgical Unit, Auckland City Hospital, Auckland, New Zealand
Received for publication December 12, 2005; revisions received January 10, 2006; accepted for publication March 13, 2006. * Address for reprints: Donald S. Likosky, PhD, Departments of Surgery and Community and Family Medicine, Dartmouth-Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756. (Email: donald.likosky@dartmouth.edu).
| The first 300 words of the full text of this article appear below. |
| Introduction |
|---|
Despite a preponderance of evidence supporting key principles of managing safe and effective CPB practice, wide variation in the use of technology and techniques for conducting CPB persists regionally and nationally.
E8,E9
Variations in practice have previously been shown to be associated with increased costs, lengths of stay, neurologic injury, and mortality.
13,E5,E10,E11
This variation might be attributed to clinical uncertainty or institutional or local practice standards. To reduce this unwanted practice variation, we must provide our clinical colleagues with critically evaluated and evidence-based review for conducting CPB.
What follows is an evidence-based review for conducting safe, patient-centered, and effective CPB practice. The authors have graded the level of evidence and classified the
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