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J Thorac Cardiovasc Surg 2006;132:455-456
© 2006 The American Association for Thoracic Surgery

Editorial

Mitral valve surgery in heart failure: Insights from the Acorn clinical trial

Eugene A. Grossi, MD*, Gregory A. Crooke, MD

Department of Cardiothoracic Surgery, NYU School of Medicine, New York, NY.

Received for publication April 27, 2006; accepted for publication May 3, 2006.

* Address for correspondence: Eugene A. Grossi, MD, New York University Medical Center, Department of Surgery, 530 First Ave, Suite 9V, Skirball Bldg, New York, NY 10016 (Email: grossi@cv.med.nyu.edu).

The first 20% of the full text of this article appears below.

GoIn this issue of the Journal, Acker and colleagues1Go present some of the outcomes of the CorCap study—specifically, the subgroup analysis of patients who underwent concomitant mitral valve surgery. In this randomized study, the addition of the CorCap device provided enhanced geometric changes in the left ventricular (LV) shape without having a significant additive effect on clinical outcomes.

The most notable information contained in this dataset is the outcomes of the control group: mitral valve surgery in medically optimized patients with significant functional mitral regurgitation, myopathic hearts, and symptomatic congestive heart failure. This subgroup represents an uncontrolled prospective analysis of isolated mitral valve surgery in patients with significant functional mitral insufficiency, New York Heart Association class III or IV, ejection fraction less than 35% (mean ejection fraction, 23% ± 9%), and a dilated LV (mean . . . [Full Text of this Article]


Related Article

Mitral valve surgery in heart failure: Insights from the Acorn Clinical Trial
Michael A. Acker, Steven Bolling, Richard Shemin, James Kirklin, Jae K. Oh, Douglas L. Mann, Mariell Jessup, Hani N. Sabbah, Randall C. Starling, Spencer H. Kubo for the Acorn Trial Principal Investigators and Study Coordinators
J. Thorac. Cardiovasc. Surg. 2006 132: 568-577. [Abstract] [Full Text] [PDF]





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