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J Thorac Cardiovasc Surg 2006;132:713-714
© 2006 The American Association for Thoracic Surgery

Brief Communication

Solitary fibrous tumor of the pleura with hypoglycemia associated with serum insulin-like growth factor II

Department of Thoracic Surgery, Shin-Kokura Hospital, Federation of National Public Service Personnel Mutual Aid Associations, Kitakyusyu, Japan.

Received for publication May 10, 2006; accepted for publication May 12, 2006.

^_* Address for reprints: Ryoichi Nakanishi, MD, PhD, Department of Thoracic Surgery, Shin-Kokura Hospital, Federation of National Public Service Personnel Mutual Aid Associations, 1-3-1 Kanada, Kokurakita-ku, Kitakyusyu 803-8505, Japan (Email: ryoichi@med.uoeh-u.ac.jp).

The first 20% of the full text of this article appears below.

Drs Nakanishi and Hirai

Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm that accounts for 10% of pleural neoplasms. Although the majority of SFTPs have benign histologic features, approximately 12% of them are malignant.¹

Although more than half of patients with SFTP are free of symptoms, large tumors cause respiratory symptoms such as dyspnea, cough, hemoptysis, and chest pain as a result of bronchial compression, atelectasis, and obstructive pneumonia. Furthermore, systemic symptoms, such as hypoglycemia and hypertrophic osteoarthropathy, and nonspecific symptoms, such as fever and fatigue, are occasionally found in patients with SFTP.

The incidence of hypoglycemia has been reported to be approximately 4%. Although insulin-like growth factor II (IGF-II) is considered to be related to the hypoglycemia, there are few reports manifesting this relationship on the basis of specific data.¹ . . . [Full Text of this Article]