JTCS KCI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Francisco Guerra
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Casati, V.
Right arrow Articles by D'Angelo, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Casati, V.
Right arrow Articles by D'Angelo, A.
Related Collections
Right arrow Coronary disease
Right arrow Extracorporeal circulation
Right arrowRelated Article

J Thorac Cardiovasc Surg 2006;132:733-734
© 2006 The American Association for Thoracic Surgery

Letter to the Editor

About the activation of the coagulation system during on-pump and off-pump coronary surgery and the use of antifibrinolytic drugs

Valter Casati, MDa, Francisco Guerra, MDb, Armando D'Angelo, MDc

a Division of Cardiovascular Anesthesia and Intensive Care, Policlinico di Monza, via Amati 111, Monza 20052, Italy
b Division of Cardiac Surgery, Policlinico di Monza, via Amati 111, Monza 20052, Italy
c Coagulation Service and Thrombosis Research Unit, Ospedale San Raffaele, Milano, Italy

(Email: valter.casati@policlinicodimonza.it).

The first 20% of the full text of this article appears below.

To the Editor:

The results of the study by Paparella and colleagues1Go recently published in the Journal confirm part of the observations described in previous reports addressing the activation of coagulation and fibrinolysis in coronary surgery performed with (ONCAB) or without (OPCAB) cardiopulmonary bypass (CPB). However, some of the statements contained in their "Discussion" section deserve critical consideration. Because no difference in tissue factor (TF) "production" was observed in the 2 groups of patients while prothrombin fragment 1.2 levels were higher in patients undergoing ONCAB, the authors state that the extrinsic pathway of coagulation should not be considered the only trigger for thrombin formation during CPB. Although the intrinsic pathway might also play a role in thrombin formation during CPB, the observation of circulating levels of TF that are not significantly different does not . . . [Full Text of this Article]


Related Article

Reply to the Editor
Domenico Paparella, Antonella Galeone, and Giuseppe Scrascia
J. Thorac. Cardiovasc. Surg. 2006 132: 734. [Extract] [Full Text] [PDF]



This article has been cited by other articles:


Home page
 Eur J Cardiothorac SurgHome page
S. F. Marasco, L. N. Sharwood, and M. J. Abramson
No improvement in neurocognitive outcomes after off-pump versus on-pump coronary revascularisation: a meta-analysis
Eur J Cardiothorac Surg, June 1, 2008; 33(6): 961 - 970.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2006 by The American Association for Thoracic Surgery.