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J Thorac Cardiovasc Surg 2006;132:988
© 2006 The American Association for Thoracic Surgery


Letter to the Editor

Candidate gene association analysis of thoracic aortic aneurysm and dissection

Usman Ahmad, MBBS, Muhammad A. Javed, MD, Saulat H. Fatimi, MD, FACS

Department of Surgery, Division of Cardiothoracic Surgery, Faculty of Health Sciences, Aga Khan University, Karach; Pakistan

The first 20% of the full text of this article appears below.

To the Editor:

In their recent article, Chen and colleagues1Go have described the association of three single-nucleotide polymorphisms of the matrix metalloproteinase 9 gene, with thoracic aortic aneurysm and dissection. One of the three single-nucleotide polymorphisms (A-8202G) was found to be associated with the disease phenotypes of aortic aneurysm and aortic dissection. Such genetic association studies are based on the presence of linkage disequilibrium in the . . . [Full Text of this Article]


Related Article

Reply to the Editor
Li Chen, Xing Li Wang, Joseph S. Coselli, and Scott A. LeMaire
J. Thorac. Cardiovasc. Surg. 2006 132: 988-989. [Extract] [Full Text] [PDF]



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X. Zhang, Y. H. Shen, and S. A. LeMaire
Thoracic Aortic Dissection: Are Matrix Metalloproteinases Involved?
Vascular, June 1, 2009; 17(3): 147 - 157.
[Abstract] [Full Text] [PDF]




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