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J Thorac Cardiovasc Surg 2006;132:1497-1498
© 2006 The American Association for Thoracic Surgery

Brief Communication

Closure of a bronchopleural fistula after extended right pneumonectomy after induction chemotherapy with BioGlue surgical adhesive

Loïc Lang-Lazdunski, MD, PhD, FRCS*

Department of Thoracic Surgery, Guy’s Hospital and King’s College, London, United Kingdom.

Received for publication June 12, 2006; accepted for publication August 8, 2006.

* Address for reprints: Loïc Lang-Lazdunski, MD, PhD, FRCS, Department of Thoracic Surgery, Guy’s Hospital, St Thomas St, London SE1 9RT, United Kingdom (Email: loic.lang-lazdunski@gstt.nhs.uk).

The first 20% of the full text of this article appears below.


Figure 1
Dr Lang-Lazdunski


Bronchopleural fistula (BPF) after pneumonectomy remains a major challenge for thoracic surgeons.1,2Go Conventional treatment combines chest tube drainage with intravenous antibiotic therapy followed by one or several of the following procedures: thoracotomy for debridement of the pleural cavity and manual closure of the bronchial stump, sternotomy and transpericardial closure of the main bronchial stump, intrathoracic transposition of a pedicled skeletal muscle or omental flap, video-assisted closure through a short cervicotomy, and open window thoracostomy.1-3Go

My colleagues and I intended to seal a BPF after right pneumonectomy using BioGlue surgical adhesive (CryoLife Inc, Kennesaw, Ga) in a patient who had received three cycles of induction chemotherapy and wished not to have any major procedure performed.

Clinical Summary

A 53-year-old woman was referred to our department with a potentially operable bronchial adenocarcinoma. Bronchoscopy, chest computed tomography, and positron emission tomography had revealed a T4 N2 M0 tumor in the right upper lobe and right main bronchus invading the superior vena cava and azygos arch (Figure 1. . . [Full Text of this Article]




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Successful Endobronchial Seal of Surgical Bronchopleural Fistulas Using BioGlue
Ann. Thorac. Surg., November 1, 2009; 88(5): 1691 - 1692.
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S. J. Keckler, T. L. Spilde, S. D. St. Peter, K. Tsao, and D. J. Ostlie
Treatment of Bronchopleural Fistula With Small Intestinal Mucosa and Fibrin Glue Sealant
Ann. Thorac. Surg., October 1, 2007; 84(4): 1383 - 1386.
[Abstract] [Full Text] [PDF]


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