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J Thorac Cardiovasc Surg 2007;133:803-804
© 2007 The American Association for Thoracic Surgery

Brief Communication

Left atrial epithelioid hemangioendothelioma

Milan Lisy, MDa, Wolfram Beierlein, MDa, Hartmut Müller, MD, PhDb, Burkhard Bültmann, MD, PhDb, Gerhard Ziemer, MD, PhDa,*

a Department of Thoracic, Cardiac and Vascular Surgery, Tübingen University Hospital, Tubingen, Germany
b Department of Pathology, Tübingen University Hospital, Tubingen, Germany.

Received for publication September 11, 2006; accepted for publication September 28, 2006.

* Address for reprints: Gerhard Ziemer, MD, PhD, Department of Thoracic, Cardiac and Vascular Surgery, Tübingen University Hospital, Hoppe-Seyler Straße 3, D-72076 Tübingen. (Email: gdziemer@uni-tuebingen.de).

The first 20% of the full text of this article appears below.

A case of cardiac epithelioid hemangioendothelioma is presented, occurring as a clinically silent pediculated left atrial tumor in a 61-year-old male patient who underwent pancreaticoduodenectomy for carcinoma of the pancreas 3 years previously. The tumor was completely resected with the presumptive clinical diagnosis of atrial myxoma. Histologic and immunohistochemical investigations demonstrated a mesenchymal tumor with antigen positivity for hemangioendotheliomas. Epithelioid hemangioendotheliomas are rare vascular tumors of the heart, histologically characterized by capillary-sized vessels lined by proliferating plump, often multilayered, epithelial-like endothelial cells with cytoplasmic vacuoles.1Go Similar to most other primary intracardiac tumors, epithelioid hemangioendotheliomas may be found incidentally or after causing congestive heart failure, pericardial effusions, outflow tract obstruction, or thromboembolic events. Because of the biologic behavior of epithelioid hemangioendotheliomas, they are regarded as fully malignant, rather than borderline neoplasms, and are to be resected radically to prevent metastatic embolic disease.

Primary cardiac tumors are rare and most commonly histologically benign, with only 30% of them exhibiting histologic signs of malignancy.2Go Clinically, they may be found incidentally by chest radiogram or by causing dysrhythmia, congestive heart failure, . . . [Full Text of this Article]




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[Abstract] [Full Text] [PDF]


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