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Toshikatsu Yagihara
Ikuo Hagino
Toru Ishizaka
Hideki Uemura
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J Thorac Cardiovasc Surg 2007;133:1101-1103
© 2007 The American Association for Thoracic Surgery

Brief Communication

Immunohistologic examination of pedicled autologous pericardium 9 years after implantation for an extracardiac conduit in Fontan pathway: Comparison with in situ pericardium and pulmonary arterial tissue from the same patient

Iki Adachi, MDa, Hatsue Ishibashi-Ueda, MDb, Toshikatsu Yagihara, MDa,*, Koji Kagisaki, MDa, Ikuo Hagino, MDa, Toru Ishizaka, MDa, Hideki Uemura, MD, FRCSc

a Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Japan
b Department of Pathology, National Cardiovascular Center, Suita, Japan
c Department of Cardio-Thoracic Surgery, Royal Brompton Hospital, London, UK.

Received for publication December 1, 2006; accepted for publication December 13, 2006.

* Address for reprints: Toshikatsu Yagihara, MD, 5-7-1 Fujishirodai, Suita, 565-8565, Japan. (Email: yagihara@hsp.ncvc.go.jp).

The first 20% of the full text of this article appears below.


Figure 1
Dr Adachi


To date there have been no clinical reports, other than our own previous report,1Go describing the histopathology of implanted pedicled autologous pericardium. Even in that report, a concern remains regarding whether the findings could correctly reflect the intrinsic properties of this tissue, because the examined tissue had been situated in apparently abnormal circumstances in which a conduit constructed with the pericardium had been compressed and occluded. Fortunately, we obtained another pedicled specimen that had been quite functional in a Fontan pathway at the time of removal. The aim of this study was to confirm the histologic characteristics of the pedicled pericardium, comparing them with our previous findings.

Clinical Summary

The patient underwent primary Fontan operation with an extracardiac conduit made with pedicled autologous pericardial roll (PAPR).2,3Go at 1 year of age. At the operation, a small piece of pulmonary arterial tissue was obtained and adequately preserved for future histologic investigation. When the patient required reoperation to relieve subaortic stenosis at . . . [Full Text of this Article]






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