J Thorac Cardiovasc Surg 2007;134:267
© 2007 The American Association for Thoracic Surgery
Intraoperative oral sildenafil for management of pulmonary hypertension: A stepping stone to the future
John G.T. Augoustides, MD, FASE, Assistant Professor
Department of Anesthesiology and Critical Care, Hospital of the University of Pennsylvania, Philadelphia, Pa
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To the Editor:
I read with great interest the recent article by Dr Shim and colleagues1
detailing their experience with oral sildenafil in intraoperative pulmonary hypertension (N = 53). Although they controlled for confounders such as anesthetic depth, hypercarbia, and serum pH, it is not clear whether they adequately controlled for hyperoxia, a potent pulmonary vasodilator.2
In their Methods section, they specify that . . . [Full Text of this Article]
Copyright © 2007 by The American Association for Thoracic Surgery.