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J Thorac Cardiovasc Surg 2007;134:810-811
© 2007 The American Association for Thoracic Surgery

Brief Communication

Overt lymph node metastases from a gastrointestinal stromal tumor of the esophagus

Takaaki Masuda, MD, PhDa, Yasushi Toh, MD, PhDa,*, Akira Kabashima, MD, PhDa, Yoshiro Aoki, MDa, Norifumi Harimoto, MD, PhDa, Shuhei Ito, MD, PhDa, Junya Taomoto, MD, PhDa, Osamu Ikeda, MD, PhDa, Takefumi Ohga, MD, PhDa, Eisuke Adachi, MD, PhDa, Yoshihisa Sakaguchi, MD, PhDa, Minako Hirahashi, MD, PhDb, Kenichi Nishiyama, MD, PhDb, Takeshi Okamura, MD, PhDa

a Department of Gastroenterogical Surgery, National Kyushu Cancer Center, Fukuoka, Japan
b Department of Pathology, National Kyushu Cancer Center, Fukuoka, Japan.

Received for publication May 23, 2007; accepted for publication June 1, 2007.

* Address for reprints: Yasushi Toh, MD, PhD, Department of Gastroenterogical Surgery, National Kyushu Cancer Center, 3-1-1, Notame, Minami-ku, Fukuoka 811-1395, Japan. (Email: ytoh@nk-cc.go.jp).

The first 20% of the full text of this article appears below.

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm with malignant potential that arises from the c-KIT (CD117)-positive intestinal cells of Cajal in the gastrointestinal tract.1Go GIST accounts for 0.1% to 3.0% of all tumors in the gastrointestinal tract and occurs in 60% of tumors in the stomach, 35% of tumors in the small bowel, and less than 1% of tumors in the esophagus.1Go Metastases of GIST commonly develop in the abdominal cavity and liver, and rarely in the lymph nodes (LNs).1,2Go The standard treatment of GIST is a complete surgical resection without a regional lymphadenectomy.3Go We describe a rare case of LN metastases from an esophageal GIST.

Clinical Summary

A 52-year-old man was hospitalized with a 1-month history of chest pain and dysphagia. His medical and family history were unremarkable. He had a 30-year history of smoking 25 cigarettes per day and occasionally drank alcohol. An esophagogastroscopy showed an ulcerated large mass partially covered with normal mucosa, which was located on the left wall of the esophagus 34 cm from the incisors. Another lesion . . . [Full Text of this Article]




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 Eur J Cardiothorac SurgHome page
P. Jiang, Z. Jiao, B. Han, X. Zhang, X. Sun, J. Su, C. Wang, and B. Gao
Clinical characteristics and surgical treatment of oesophageal gastrointestinal stromal tumours
Eur J Cardiothorac Surg, August 1, 2010; 38(2): 223 - 227.
[Abstract] [Full Text] [PDF]


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