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J Thorac Cardiovasc Surg 2007;134:814-815
© 2007 The American Association for Thoracic Surgery

Brief Communication

Lung transplantation in Kartagener syndrome and situs inversus: Potential of multidetector row computed tomography and three-dimensional postprocessing

Thomas Schertler, Dr meda,*, Didier Lardinois, PD, Dr medb, Thomas Boehm, PD, Dr meda, Walter Weder, Prof, Dr medb, Simon Wildermuth, PD, Dr meda, Hatem Alkadhi, PD, Dr meda

a Institute of Diagnostic Radiology, University Hospital Zurich, Switzerland
b Division of Thoracic Surgery, Department of Surgery, University Hospital Zurich, Switzerland.

Received for publication March 23, 2007; revisions received May 8, 2007; accepted for publication May 11, 2007.

* Address for reprints: Dr med Thomas Schertler, Institute of Diagnostic Radiology, University Hospital Zurich, Raemistrasse 100, CH-8091 Zurich, Switzerland. (Email: thomas.schertler@usz.ch).

The first 20% of the full text of this article appears below.

Kartagener syndrome is a rare congenital genetic disorder that is characterized by the triad situs inversus, bronchiectasis, and sinusitis.1Go Patients have defective ciliary motility that leads to reduced or absent mucus clearance in the lungs and susceptibility to chronic respiratory infections. Lung transplantation has been shown to be effective in cases of severe respiratory failure. Only a few cases of lung transplantation in patients with Kartagener syndrome have been reported so far.2Go

Multidetector row computed tomography (MDCT) represents the principal diagnostic modality for the assessment of bronchopulmonary and cardiovascular anatomy. Recent developments of MDCT technology, including CT angiography (CTA), enable the acquisition of near-isotropic datasets representing the prerequisite for 2- and 3-dimensional (2D and 3D) postprocessing techniques.

We describe the case of a patient with Kartagener syndrome in whom MDCT with 2D and 3D postprocessing allowed a precise visualization of bronchopulmonary and cardiovascular morphologic characteristics before and after lung transplantation.

Clinical Summary

The diagnosis of Kartagener syndrome with situs inversus totalis thoracalis et abdominalis was made in a 59-year-old patient at the age of 19 years. At the age of 13 years, a lower bilobectomy (middle and lower lobes) was performed on the left side . . . [Full Text of this Article]






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