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J Thorac Cardiovasc Surg 2007;134:1092-1093
© 2007 The American Association for Thoracic Surgery

Brief Communication

Living-donor single-lobe lung transplantation for bronchiolitis obliterans in a 4-year-old boy

^a Department of Surgery, Division of Thoracic Surgery, Fukuoka University Hospital, Fukuoka City, Japan
^b Department of Anesthesiology, Fukuoka University Hospital, Fukuoka City, Japan
^c Department of Respiratory Medicine, Fukuoka University Hospital, Fukuoka City, Japan
^d Department of Cardiovascular Surgery, Fukuoka University Hospital, Fukuoka City, Japan
^e Department of Pathology, Fukuoka University Hospital, Fukuoka City, Japan
^f Department of Surgery II, Oita University Hospital, Oita, Japan
^g Department of Thoracic Surgery, National Fukuoka-Higashi Medical Center, Koga City, Japan
^h Department of Cardiovascular Surgery, Saint Mary Hospital, Kurume City, Japan.

Received for publication February 18, 2007; accepted for publication March 29, 2007.

^_* Address for reprints: Takeshi Shiraishi, MD, Department of Surgery, Division of Thoracic Surgery, Fukuoka University Hospital, 7-5-41 Nanakuma, Jonan-ku, Fukuoka City, Fukuoka, 814-0180 Japan. (Email: tshiraishi-ths@umin.ac.jp).

The first 20% of the full text of this article appears below.

Drs Shiraishi and Shirakusa (left to right)

A single-lobe lung transplantation from a living donor was performed in a 4-year-old boy. The transplantation was successful, and the patient recovered smoothly despite severe volume mismatch between the lung allograft and the recipient chest cavity. To our knowledge, this case represents the youngest recipient of a living-related single-lobe transplantation ever reported.

Clinical Summary

This male patient’s history included diagnosis of juvenile myelomonocytic leukemia at 1 year 3 months, with subsequent peripheral blood stem cell transplantation from his mother. He later had bronchiolitis obliterans develop, and his respiratory condition progressively deteriorated thereafter. Mechanical ventilation was instituted at 4 years 10 months because of the onset of carbon dioxide narcosis. Chest computed tomography (CT) demonstrated bilateral diffuse emphysema and severe lung overexpansion.

Transplantation from a cadaveric donor is considered impossible within a limited time frame; therefore, the only realistic transplant option was considered a living-related single-lobe lung transplantation (because of the recipient’s small stature). The potential donor was his mother. The heights . . . [Full Text of this Article]

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