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J Thorac Cardiovasc Surg 2007;134:1371-1372
© 2007 The American Association for Thoracic Surgery


Brief Communication

Dissection of a mediastinal mature teratoma requires replacement of the ascending aorta during cardiopulmonary bypass

Satoru Kobayashi, MD, PhD*, Noriyoshi Sawabata, MD, PhD, Osamu Araki, MD, Yoko Karube, MD, PhD, Norio Seki, MD, Motohiko Tamura, MD, PhD, Hideo Umezu, MD, Hiromi Ishihama, MD, Sensuke Nagai, MD, PhD, Shinichiro Miyoshi, MD, PhD

Department of Cardiothoracic Surgery, Dokkyo University School of Medicine, Tochigi, Japan.

Received for publication March 13, 2007; accepted for publication April 23, 2007.

* Address for reprints: Satoru Kobayashi, MD, Department of Cardiothoracic Surgery, Dokkyo University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan. (Email: kobayasi@dokkyomed.ac.jp).

The first 20% of the full text of this article appears below.

A mediastinal mature teratoma occasionally ruptures into adjacent organs and causes various complications, although such a rupture into the ascending aorta is extremely rare. We report a case complicated by perforation of the aorta during an operation that required replacement of the aorta with an artificial graft and discuss the pathophysiology of the perforation.

Clinical Summary

A 25-year-old woman with substernal chest pain visited a local clinic in June 2003, during which time chest radiographic and electrocardiographic findings did not reveal any abnormalities. At 1 year and 3 months later, the patient visited another clinic with more severe and progressing symptoms, from which she was referred to our hospital for further investigation of an abnormal shadow on a chest X-ray image.

The patient had no notable past or family history. Systolic cardiac murmurs were auscultated in the third intercostal space in the left sternal border. A laboratory study demonstrated inflammatory findings of leukocytosis of 1.2 x 109/L, increase of C reactive protein level to 4.6 mg/dL, and increase of carcinogenetic antigen 19-9 level to 585 U/mL. Chest computed . . . [Full Text of this Article]







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