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J Thorac Cardiovasc Surg 2008;135:299
© 2008 The American Association for Thoracic Surgery

Invited Commentary

Discussion

The first 20% of the full text of this article appears below.

Dr Y. Joseph Woo (Philadelphia, Pa). You should be congratulated for a fantastic study, particularly with the technical aspects that you showed and also the creative water bath assay. You answered a lot of the potential questions that the audience would have with in your last two slides.

Your study is very good at showing the effects of your therapy. To take your study to the next level, you should show some mechanistic components. The investigators who are doing a lot of the stem cell transplantation work are thinking that there is not much cross-linking of the cells and probably not a tremendous contractile contribution from stem cell transplantation, but rather some sort of biofactory effect. You did measure a multitude of different parameters. Can you comment on some of the other things that you may . . . [Full Text of this Article]






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