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J Thorac Cardiovasc Surg 2008;135:997-998
© 2008 The American Association for Thoracic Surgery


Invited Commentary

Discussion

The first 20% of the full text of this article appears below.

Dr Robert C. Gorman (Philadelphia, Pa). This is an interesting and potentially important study because you are trying to assess how mechanical events in the heart that occur after an infarct affect the biology of the remaining normally perfused myocardium.

As surgeons, we have focused primarily on influencing those geometric properties with our surgical treatments for heart failure, with the tacit assumption that the remaining myocardium is inherently normal. This line of work is very important because it may help to explain why our results for surgical heart failure are not as good as we would expect after we return the heart to normal geometry, being that the existing myocardium has some inherent changes in it that have altered it beyond surgical repair.

That being said, I have 2 questions in regard to the technical performance . . . [Full Text of this Article]


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Regional remodeling strain and its association with myocardial apoptosis after myocardial infarction in an ovine model
Godfred K. Yankey, Tieluo Li, Ahmet Kilic, Guangming Cheng, Aditee Satpute, Kinjal Savai, Shuying Li, Sina L. Moainie, Deyanira Prastein, Christopher DeFillipi, Zhongjun J. Wu, and Bartley P. Griffith
J. Thorac. Cardiovasc. Surg. 2008 135: 991-998. [Abstract] [Full Text] [PDF]






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