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J Thorac Cardiovasc Surg 2008;135:1392-1394
© 2008 The American Association for Thoracic Surgery

Brief Communication

A meta-analysis of comparative studies of endovascular versus open repair for blunt thoracic aortic injury

Department of Cardiovascular Surgery, Shizuoka Medical Center, Shizuoka, Japan

Received for publication December 19, 2007; accepted for publication January 13, 2008.

^_* Address for reprints: Hisato Takagi, MD, PhD, Department of Cardiovascular Surgery, Shizuoka Medical Center, 762-1 Nagasawa, Shimizu-cho, Sunto-gun, Shizuoka 411-8611, Japan. (Email: kfgth973@ybb.ne.jp).

The first 20% of the full text of this article appears below.

Several recent comparative studies^1-5 of endovascular (EVR) versus open repair (OR) for blunt thoracic aortic injury (BTAI) suggest that EVR may be associated with a reduction in mortality. Such comparisons are, however, hampered by the small number of cases, owing to the relative rarity of this condition.⁴ Therefore, the appropriate role of EVR for BTAI remains unclear. We performed a meta-analysis of all comparative studies of EVR versus OR for BTAI to date.

Materials and Methods

All comparative studies of EVR versus OR for BTAI were identified by a 2-level search strategy. First, a public domain database (MEDLINE) was searched using a Web-based search engine (PubMed). Second, relevant studies were identified through a manual search of secondary sources including references of initially identified articles and a search of reviews and commentaries. The MEDLINE database was searched from January 1966 to December 2007. MeSH keywords included "Aortic Rupture," "Aorta," "Wounds and Injuries," "Aortic Aneurysm, Thoracic," "Stents," and "Comparative Study." Studies considered for inclusion met the following criteria: the design was a comparative study of EVR versus OR; the study population was patients with BTAI; and main outcomes included mortality. Data regarding detailed inclusion criteria and mortality were abstracted (as available) from each individual study. For each study, data regarding mortality in both the EVR and OR groups were used to generate odds ratios and 95% confidence intervals (CIs). Study-specific . . . [Full Text of this Article]

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